Cannabidiol (CBD) is a naturally occurring cannabinoid constituent of cannabis. It was discovered in 1940 and initially thought to not be pharmaceutically active. It is one of at least 113 cannabinoids identified in hemp plants, accounting for up to 40% of the plant’s extract.
The law as written requires physicians to “prescribe” CBD, which would break federal law. States with legal programs allow doctors to “recommend” as opposed to prescribe. However, the Texas Compassionate Use Program says that “prescription” is defined as “an entry in the compassionate-use registry” and three dispensing organizations had been licensed as of Dec. 15, 2017.
Our hemp extracts may be extremely low in THC, but they are rich in terpenes. Terpenes are organic compounds and isomeric hydrocarbons (C10H16) found within hemp flower excretions. At Bluebird Botanicals, we develop the genetics for our hemp in highly-specialized Colorado greenhouses and source our crops from outdoor farms, which use organic growing methods and no pesticides. These farms cultivate specialty high-terpene hemp plants specifically bred to for the production of hemp and CBD oil.
Jump up ^ Zlebnik, N. E; Cheer, J. F (2016). “Beyond the CB1 Receptor: Is Cannabidiol the Answer for Disorders of Motivation?”. Annual Review of Neuroscience. 39: 1–17. doi:10.1146/annurev-neuro-070815-014038. PMC 5818147 . PMID 27023732.
The use of medical marijuana continues to be an emotionally and politically charged issue. Although cannabis oil preparations have been used in medicine for millennia, the concern over the dangers of abuse led to the banning of the medicinal use of marijuana in the 1930s.
Cannabigerol: When olivetolic acid and Geranyl pyrophosphate combine in the plants, they produce cannabigerolic acid. Many cannabinoids are made from cannabigerolic acid (CBGA). CBG, one of the phyto-cannabinoids found in our extracts, is essentially the same as CBGA, but in non-acidic form.
We’ve systematically sought out the most beautiful and healthy hemp cultivars for our raw ingredients used in manufacturing, and we always test for purity and potency. Hemp, because of its innate ability to thrive easily, doesn’t require pesticides (the aromatic terpene compounds in hemp can actually act as natural pesticides), fertilizers, or herbicides in its cultivation, and requires much less water than standard commercial farming. The hemp we use is grown under the same methods and standards of organic farming.
A 2014 survey conducted by researchers at Stanford University was presented to parents belonging to a Facebook group dedicated to sharing information about the use of cannabidiol-enriched cannabis to treat their child’s seizures. Nineteen responses met the inclusion criteria for the study: a diagnosis of epilepsy and current use of CBD-enriched cannabis. The average number of anti-epileptic drugs tried before using CBD cannabis was 12. Sixteen (84 percent) of the 19 parents reported a reduction in their child’s seizure frequency while taking CBD cannabis. Of these, two (11 percent) reported complete seizure freedom, eight (42 percent) reported a greater than 80 percent reduction in seizure frequency, and six (32 percent) reported a 25–60 percent seizure reduction. Other beneficial effects included increased alertness, better mood and improved sleep; while side effects included drowsiness and fatigue. (14)
I purchased the 600 mg of pure kana. Overall i can say this has made a huge difference in my social life. I have not felt any kind of anxiety since taking the drops. I am about a month and a half in and on my second bottle. I wish purekana offered some kind of bundle deals or reward program since I know this is something worth purchasing monthly. Its always nice to save a little ?
Don’t order if you need it within a few weeks. Ordered 5 days ago and no word on when it will ship. Hoping to get a response to my email on Monday (a week after I ordered) but at the point it will take 2 weeks to get it- if I get it! Was excited to try this brand as I’ve heard great reviews. Unfortunately the slow shipping and no updates (in case something is wrong- I don’t see the vanilla even listed anymore) has left a pretty bad first impression.
Blessing, E. M., Steenkamp, M. M., Manzanares, J., & Marmar, C. R. (2015, October). Cannabidiol as a potential treatment for anxiety disorders. Neurotherapeutics, 12(4), 825-836. Retrieved from www.ncbi.nlm.nih.gov/pmc/articles/PMC4604171/
Worse, CBD is being produced without any regulation, resulting in products that vary widely in quality, said Marcel Bonn-Miller, an adjunct assistant professor of psychology in psychiatry at the University of Pennsylvania School of Medicine.
CBD is one of more than 80 active cannabinoid chemicals in the marijuana plant.ii Unlike the main psychoactive cannabinoid in marijuana, tetrahydrocannabinol (THC), CBD does not produce euphoria or intoxication.iii,iv,v Cannabinoids have their effect mainly by interacting with specific receptors on cells in the brain and body: the CB1 receptor, found on neurons and glial cells in various parts of the brain, and the CB2 receptor, found mainly in the body’s immune system. The euphoric effects of THC are caused by its activation of CB1 receptors. CBD has a very low affinity for these receptors (100 fold less than THC) and when it binds it produces little to no effect. There is also growing evidence that CBD acts on other brain signaling systems, and that these actions may be important contributors to its therapeutic effects.ii
CBD oil is the short form of the term cannabidiol oil. Cannabidiol is a natural component of industrial cannabis or hemp. CBD oil is cannabis oil that has a significant content of cannabidiol. It is made from the flowers, leaves and stalks of hemp and not from its seeds like hemp oil. CBD oil has become very popular in the medical marijuana industry, because it can be helpful in the treatment of various conditions without the typical intoxicating effects of marijuana use.
Consroe, P., Laguna, J., Allender, J., Snider, S., Stern, L., Sandyk, R., Kennedy, K., and Schram, K. Controlled clinical trial of cannabidiol in Huntington’s disease. Pharmacol Biochem.Behav. 1991;40(3):701-708. View abstract.
In addition to CBD, Cannabis sativa L contains organic compounds called terpenes. Terpenes are isomeric hydrocarbons (C10H16) used to create essential oils, balsams, and other by-products. When chemically modified through oxidation or other methods, terpenes become terpenoids (sometimes referred to as isoprenoids). Vitamin A is one example of a terpenoid.
The compound has also shown promise in treating anxiety, depression and schizophrenia. Much of this work has been in rats and mice, but several studies have found benefits for humans. For instance, German researchers showed in 2012 that giving CBD to schizophrenic patients reduced psychotic symptoms such as hallucinations and disordered thinking.
Longer answer: Hemp and marijuana are both cannabis, and both work with the endocannabinoid system in the body, but there are a few key differences. Marijuana has a high concentration of THC – the cannabinoid that makes you feel “high”. Hemp has a very low concentration of THC (less than 0.3%), does not get you high, and is legal in all 50 states without a medical marijuana card. Hemp has a much higher concentration of CBD than marijuana, as well as numerous of other cannabinoids that work with your endocannabinoid system to bring about greater overall health and vitality.
The Food and Drug Administration on 6/25/2018 approved the first drug derived from marijuana, which will be used to treat two rare and severe forms of childhood epilepsy. FDA Commissioner Scott Gottlieb said the approval was “a reminder that advancing sound development programs that properly evaluate active ingredients contained in marijuana can lead to important medical therapies.” He noted that the action was “not an approval of marijuana or all of its components” but rather of one specific CBD medication for a particular use. In April, an advisory committee unanimously recommended approval of the drug for the two types of epilepsy.
According to the Utah Department of Health Hemp Registry, “To legally possess hemp extract under Utah law, an individual must apply for and obtain a hemp extract registration card from the Utah Department of Health, Office of Vital Records and Statistics (OVRS)”
CBD Oil Grand Lake CO | Where Can You Purchase Near Me
About CBD Oil Grand Lake CO | Where Can You Purchase In August, 2017
I bought a trial size and the first day I felt uplifted about 20 minutes or less after I took it. I have Fibromyalgia which means my back, head and other areas of my body is sensitive to touch., I have scoliosis and chodromalatia patella in both knees. When I had to cut back on my medication,I was scared I would suffer. I already have low energy and a bit of depression because of this and pain. But this CBD oil is worth every penny. (Thank you so much for keeping it on sale ). I have my energy back that I had 10 years ago, My pain is tolerable and I can do things with my 12 grandchildren. I’m not so grouchy and For the first time in A LONG time, my house is getting cleaned and organized like it used to be. You won’t be sorry. Just try it. Pure kana is the only one I’ve tried but I won’t go elsewhere, they are rated in the top 5 pure and natural. PLEASE KEEP UP THE WONDERFUL WORK! ! Thank you do much
We sell Companion Capsules and Companion Oil to keep pets healthy. The capsules contain 15+mg cannabinoid per capsule blended with organic hemp seed oil. The Companion Oil contains 250+ mg cannabinoids per fluid ounce for a hemp extract that’s both terpene-rich and legal for dogs, cats, and other pets.
Marijuana can produce acute psychotic episodes at high doses, and several studies have linked marijuana use to increased risk for chronic psychosis in individuals with specific genetic risk factors. Research suggests that these effects are mediated by THC, and it has been suggested that CBD may mitigate these effects.xxxi There have been a few small-scale clinical trials in which patients with psychotic symptoms were treated with CBD, including case reports of patients with schizophrenia that reported conflicting results; a small case study in patients with Parkinson’s disease with psychosis, which reported positive results; and one small randomized clinical trial reporting clinical improvement in patients with schizophrenia treated with CBD.xxxii Large randomized clinical trials would be needed to fully evaluate the therapeutic potential of CBD for patients with schizophrenia and other forms of psychosis.
Best kept refrigerated (can be left out of the fridge, too). Most people swallow 15 drops or more, as desired. The amount of Hemp Classic that people take on a daily basis can vary greatly. It can be taken day or night, preferably after a meal.
A cannabis oil of extracted industrial hemp that is abundant in naturally occurring cannabinoids, terpenes, vitamins, omega fatty acids, trace minerals and other beneficial components, emulsified in organic hemp seed oil.
Malone DT, Jongejan D, Taylor DA. Cannabidiol reverses the reduction in social interaction produced by low dose Delta(9)-tetrahydrocannabinol in rats. Pharmacol Biochem Behav 2009;93(2):91-6. View abstract.
CBD (Cannabidiol) is a prominent, non-psychoactive cannabinoid found in hemp. It is generally extracted from hemp plants that are naturally high in CBD and other phytochemicals. There are over 80 different cannabinoids found in hemp. It is commonly used for its therapeutic properties.
On July 1, 2015, HB 32became law after Gov. Matt Mead neither signed the bill nor vetoed it, allowing the use of hemp extract that contains at least 15% CBD and no more than 0.3% THC for the treatment of intractable epilepsy.
There is significant preliminary research supporting the potential therapeutic value of CBD, and while it is not yet sufficient to support drug approval, it highlights the need for rigorous clinical research in this area. There are barriers that should be addressed to facilitate more research in this area. We appreciate the opportunity to testify on the potential use of CBD for therapeutic purposes. Thank you again for inviting me here today, and I look forward to any questions you may have.
Some people feel that CBD offers a more natural way to lower pain. A study published in the Journal of Experimental Medicine found that CBD significantly reduced chronic inflammation and pain in some mice and rats.
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